Molecular characterisation of NPM1 and FLT3-ITD mutations in a central South African adult de novo acute myeloid leukaemia cohort

Molecular characterisation of NPM1 and FLT3-ITD mutations in a central South African adult de novo acute myeloid leukaemia cohort

Background: Recognition of molecular abnormalities in acute myeloid leukaemia (AML) has improved our understanding of its biology. NPM1 and FLT3-ITD mutations are recurrent in AML and clinically significant. NPM1 mutations are associated with a favourable prognosis, while FLT3-ITD mutations are an i...

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Bibliographic Details
Main Authors: Jean F. Kloppers, André de Kock, Johané Cronjé, Anne-Cecilia van Marle
Format: Article
Language:English
Published: AOSIS 2021-06-01
Series:African Journal of Laboratory Medicine
Subjects:
acute myeloid leukaemia
aml
npm1
flt3-itd
frequency
south africa
Online Access:https://ajlmonline.org/index.php/ajlm/article/view/1363

Internet

https://ajlmonline.org/index.php/ajlm/article/view/1363

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