Targeting Human α-Lactalbumin Gene Insertion into the Goat β-Lactoglobulin Locus by TALEN-Mediated Homologous Recombination.

Special value of goat milk in human nutrition and well being is associated with medical problems of food allergies which are caused by milk proteins such as β-lactoglobulin (BLG). Here, we employed transcription activator-like effector nuclease (TALEN)-assisted homologous recombination in goat fibro...

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Bibliographic Details
Main Authors: Hongmei Zhu, Jun Liu, Chenchen Cui, Yujie Song, Hengtao Ge, Linyong Hu, Qian Li, Yaping Jin, Yong Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4892491?pdf=render