Overexpression of Interferon-Inducible Protein 16 Promotes Progression of Human Pancreatic Adenocarcinoma Through Interleukin-1β-Induced Tumor-Associated Macrophage Infiltration in the Tumor Microenvironment

Overexpression of Interferon-Inducible Protein 16 Promotes Progression of Human Pancreatic Adenocarcinoma Through Interleukin-1β-Induced Tumor-Associated Macrophage Infiltration in the Tumor Microenvironment

Activation of inflammasomes has been reported in human pancreatic adenocarcinoma (PAAD); however, the expression pattern and functional role of inflammasome-related proteins in PAAD have yet to be identified. In this study, we systemically examined the expression and role of different inflammasome p...

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Bibliographic Details
Main Authors: Jing-Xian Chen, Chien-Shan Cheng, Hong-Fang Gao, Zi-Jie Chen, Ling-Ling Lv, Jia-Yue Xu, Xiao-Heng Shen, Jing Xie, Lan Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
IFI16
inflammasome
pancreatic adenocarcinoma
tumor-associated macrophages
IL-1β
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.640786/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.640786/full

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