Viral Restriction Activity of Feline BST2 Is Independent of Its N-Glycosylation and Induction of NF-κB Activation.

BST2 (CD317, tetherin, HM1.24) is an interferon-inducible transmembrane protein which can directly inhibit the release of enveloped virus particles from infected cells, and its anti-viral activity is reported to be related to the specific topological arrangement of its four structural domains. The N...

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Bibliographic Details
Main Authors: Weiran Wang, Jiawen Wang, Meng Qu, Xiaojun Li, Jingyao Zhang, Haihong Zhang, Jiaxin Wu, Bin Yu, Hui Wu, Wei Kong, Xianghui Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4574558?pdf=render