The influence of neuronal density and maturation on network activity of hippocampal cell cultures: a methodological study.

It is known that cell density influences the maturation process of in vitro neuronal networks. Neuronal cultures plated with different cell densities differ in number of synapses per neuron and thus in single neuron synaptic transmission, which results in a density-dependent neuronal network activit...

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Bibliographic Details
Main Authors: Emilia Biffi, Giulia Regalia, Andrea Menegon, Giancarlo Ferrigno, Alessandra Pedrocchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3873984?pdf=render