Systematic screening of 96 Schistosoma mansoni cell-surface and secreted antigens does not identify any strongly protective vaccine candidates in a mouse model of infection [version 1; peer review: 2 approved]

Background: Schistosomiasis is a major parasitic disease affecting people living in tropical and sup-tropical areas. Transmission of the parasite has been reported in 78 countries, causing significant morbidity and around 200,000 deaths per year in endemic regions. The disease is currently managed b...

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Bibliographic Details
Main Authors: Cecile Crosnier, Cordelia Brandt, Gabriel Rinaldi, Catherine McCarthy, Colin Barker, Simon Clare, Matthew Berriman, Gavin J. Wright
Format: Article
Language:English
Published: Wellcome 2019-10-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/4-159/v1