Absence of an embryonic stem cell DNA methylation signature in human cancer
Abstract Background Differentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture of cell types that are of fetal ori...
Main Authors: | Ze Zhang, John K. Wiencke, Devin C. Koestler, Lucas A. Salas, Brock C. Christensen, Karl T. Kelsey |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12885-019-5932-6 |
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