Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity.

In spite of its highly immunogenic properties, Mycobacterium tuberculosis (Mtb) establishes persistent infection in otherwise healthy individuals, making it one of the most widespread and deadly human pathogens. Mtb's prolonged survival may reflect production of microbial factors that prevent e...

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Bibliographic Details
Main Authors: Aimee M Beaulieu, Poonam Rath, Marianne Imhof, Mark E Siddall, Julia Roberts, Dirk Schnappinger, Carl F Nathan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3000826?pdf=render