EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferation.

EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferation.

Epstein-Barr virus (EBV), a ubiquitous human herpesvirus, can latently infect the human population. EBV is associated with several types of malignancies originating from lymphoid and epithelial cell types. EBV latent antigen 3C (EBNA3C) is essential for EBV-induced immortalization of B-cells. The Mo...

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Bibliographic Details
Main Authors: Shuvomoy Banerjee, Jie Lu, Qiliang Cai, Zhiguo Sun, Hem Chandra Jha, Erle S Robertson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4133388?pdf=render

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http://europepmc.org/articles/PMC4133388?pdf=render

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