Role of PTPα in the destruction of periodontal connective tissues.

Role of PTPα in the destruction of periodontal connective tissues.

IL-1β contributes to connective tissue destruction in part by up-regulating stromelysin-1 (MMP-3), which in fibroblasts is a focal adhesion-dependent process. Protein tyrosine phosphatase-α (PTPα) is enriched in and regulates the formation of focal adhesions, but the role of PTPα in connective tissu...

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Bibliographic Details
Main Authors: Dhaarmini Rajshankar, Corneliu Sima, Qin Wang, Stephanie R Goldberg, Mwayi Kazembe, Yongqiang Wang, Michael Glogauer, Gregory P Downey, Christopher A McCulloch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3734242?pdf=render

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http://europepmc.org/articles/PMC3734242?pdf=render

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