Cell-Penetrating Penta-Peptides (CPP5s): Measurement of Cell Entry and Protein-Transduction Activity

Cell-Penetrating Penta-Peptides (CPP5s): Measurement of Cell Entry and Protein-Transduction Activity

Previously, we developed cell-penetrating penta-peptides (CPP5s). In the present study, VPTLK and KLPVM, two representative CPP5s, were used to characterize the cell-penetration and protein-transduction activities of these small molecules. Various inhibitors of endocytosis and pinocytosis (chlorprom...

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Bibliographic Details
Main Authors: Masaru Miyagi, Shigemi Matsuyama, Justine Ngo, Dagmar Hajkova, I-Ju Yeh, Vivian Gama, Jose A. Gomez, Joseph Chen
Format: Article
Language:English
Published: MDPI AG 2010-12-01
Series:Pharmaceuticals
Subjects:
Cell-Penetrating Peptide (CPP), Cell-Penetrating Penta-peptide (CPP5), Bax Inhibiting Peptide (BIP), Protein Transduction, Ku70, Bax, Apoptosis, Drug Delivery
Online Access:http://www.mdpi.com/1424-8247/3/12/3594/

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http://www.mdpi.com/1424-8247/3/12/3594/

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