Plasma from patients with anti-glomerular basement membrane disease could recognize microbial peptides.

Infection has long been suspected as a trigger of autoimmune diseases, and molecular mimicry mechanism was hypothesized in this study. Microbe originated peptides were searched from the Uniprot database based on a previous defined critical amino acid motif within α3129-150, isoleucine137, tryptophan...

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Bibliographic Details
Main Authors: Jian-Nan Li, Xiaoyu Jia, Yongqiang Wang, Can Xie, Taijiao Jiang, Zhao Cui, Ming-Hui Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5391914?pdf=render