Dietary Fructose Feeding Increases Adipose Methylglyoxal Accumulation in Rats in Association with Low Expression and Activity of Glyoxalase-2

Methylglyoxal is a precursor to advanced glycation endproducts that may contribute to diabetes and its cardiovascular-related complications. Methylglyoxal is successively catabolized to d-lactate by glyoxalase-1 and glyoxalase-2. The objective of this study was to determine whether dietary fructose...

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Bibliographic Details
Main Authors: Richard S. Bruno, Sung I. Koo, Youngki Park, Sang K. Noh, Jiyoung Lee, Christopher Masterjohn
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/5/8/3311