Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1

Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1

Abstract Background Somatic cell reprogramming is the process that allows differentiated cells to revert to a pluripotent state. In contrast to the extensively studied rewiring of epigenetic and transcriptional programs required for reprogramming, the dynamics of post-transcriptional changes and the...

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Bibliographic Details
Main Authors: Claudia Vivori, Panagiotis Papasaikas, Ralph Stadhouders, Bruno Di Stefano, Anna Ribó Rubio, Clara Berenguer Balaguer, Serena Generoso, Anna Mallol, José Luis Sardina, Bernhard Payer, Thomas Graf, Juan Valcárcel
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Genome Biology
Subjects:
Alternative splicing
Somatic cell reprogramming
CPSF3
hnRNP UL1
TIA1
Pluripotency
Online Access:https://doi.org/10.1186/s13059-021-02372-5

Internet

https://doi.org/10.1186/s13059-021-02372-5

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