Impact of Different Mucoadhesive Polymeric Nanoparticles Loaded in Thermosensitive Hydrogels on Transcorneal Administration of 5-Fluorouracil

Impact of Different Mucoadhesive Polymeric Nanoparticles Loaded in Thermosensitive Hydrogels on Transcorneal Administration of 5-Fluorouracil

In a previous paper a thermosensitive hydrogel formulation based on chitosan or its derivatives (TSOH), containing medicated chitosan nanoparticles (Ch NP) for transcorneal administration of 5-fluorouracil (5-FU) was described. The Ch NP-containing TSOH allowed a time-constant 5-FU concentration in...

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Bibliographic Details
Main Authors: Angela Fabiano, Anna Maria Piras, Lorenzo Guazzelli, Barbara Storti, Ranieri Bizzarri, Ylenia Zambito
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Pharmaceutics
Subjects:
thermosensitive hydrogels
mucoadhesive chitosan multifunctional derivatives
mucoadhesive nanoparticles
ocular cancer
microrheology
ocular delivery
Online Access:https://www.mdpi.com/1999-4923/11/12/623

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https://www.mdpi.com/1999-4923/11/12/623

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