Achieving high accuracy prediction of minimotifs.

The low complexity of minimotif patterns results in a high false-positive prediction rate, hampering protein function prediction. A multi-filter algorithm, trained and tested on a linear regression model, support vector machine model, and neural network model, using a large dataset of verified minim...

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Bibliographic Details
Main Authors: Tian Mi, Sanguthevar Rajasekaran, Jerlin Camilus Merlin, Michael Gryk, Martin R Schiller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3459956?pdf=render