Design and effective synthesis of novel furo[2,3-d]pyrimidine derivatives containing ethylene ether spacers

Design and effective synthesis of novel furo[2,3-d]pyrimidine derivatives containing ethylene ether spacers

[1+4] Cycloaddition reaction of ethylene ether-based N,N-dimethybenzylidenebarbituric acid with alkyl isocyanide in DMF produced novel high substituted furo[2,3-d]pyrimidine derivatives containing ether spacers under mild reaction conditions. The structures of the products were deduced from their IR...

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Bibliographic Details
Main Author: Enayatollah Sheikhhosseini
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Saudi Chemical Society
Subjects:
Alkyl isocyanide
Furo[2,3-d]pyrimidine
Ethylene ether spacer
Arylidenebarbituric acid
Antibacterial activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610316300382

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http://www.sciencedirect.com/science/article/pii/S1319610316300382

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