Estrogen receptor β exerts tumor repressive functions in human malignant pleural mesothelioma via EGFR inactivation and affects response to gefitinib.

Estrogen receptor β exerts tumor repressive functions in human malignant pleural mesothelioma via EGFR inactivation and affects response to gefitinib.

BACKGROUND: The role of estrogen and estrogen receptors in oncogenesis has been investigated in various malignancies. Recently our group identified estrogen receptor beta (ERβ) expression as an independent prognostic factor in the progression of human Malignant Pleural Mesothelioma (MMe), but the un...

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Bibliographic Details
Main Authors: Giulia Pinton, Warren Thomas, Paolo Bellini, Arcangela Gabriella Manente, Roberto E Favoni, Brian J Harvey, Luciano Mutti, Laura Moro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2993924?pdf=render

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http://europepmc.org/articles/PMC2993924?pdf=render

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