Protein C inhibitor--a novel antimicrobial agent.

Protein C inhibitor--a novel antimicrobial agent.

Protein C inhibitor (PCI) is a heparin-binding serine proteinase inhibitor belonging to the family of serpin proteins. Here we describe that PCI exerts broad antimicrobial activity against bacterial pathogens. This ability is mediated by the interaction of PCI with lipid membranes, which subsequentl...

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Bibliographic Details
Main Authors: Erik Malmström, Matthias Mörgelin, Martin Malmsten, Linda Johansson, Anna Norrby-Teglund, Oonagh Shannon, Artur Schmidtchen, Joost C M Meijers, Heiko Herwald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20019810/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20019810/?tool=EBI

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