Ginsenoside Rh2 Ameliorates Lipopolysaccharide-Induced Acute Lung Injury by Regulating the TLR4/PI3K/Akt/mTOR, Raf-1/MEK/ERK, and Keap1/Nrf2/HO-1 Signaling Pathways in Mice

Ginsenoside Rh2 Ameliorates Lipopolysaccharide-Induced Acute Lung Injury by Regulating the TLR4/PI3K/Akt/mTOR, Raf-1/MEK/ERK, and Keap1/Nrf2/HO-1 Signaling Pathways in Mice

The anti-inflammatory effect of ginsenoside Rh2 (GRh2) has labeled it as one of the most important ginsenosides. The purpose of this study was to identify the anti-inflammatory and antioxidant effects of GRh2 using a lipopolysaccharide (LPS) challenge lung-injury animal model. GRh2 reduced LPS-induc...

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Bibliographic Details
Main Authors: Yung-Hung Hsieh, Jeng-Shyan Deng, Yuan-Shiun Chang, Guan-Jhong Huang
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Nutrients
Subjects:
ginsenoside Rh2
lipopolysaccharide
acute lung injury
MEK
Nrf-2
Online Access:http://www.mdpi.com/2072-6643/10/9/1208

Internet

http://www.mdpi.com/2072-6643/10/9/1208

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