HLA-Bw4-B*57 and Cw*18 alleles are associated with plasma viral load modulation in HIV-1 infected individuals in Salvador, Brazil

HLA-Bw4-B*57 and Cw*18 alleles are associated with plasma viral load modulation in HIV-1 infected individuals in Salvador, Brazil

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Host genetic factors play an important role in mediating resistance to HIV-1 infection and may modify the course of infection. HLA-B alleles (Bw4 epitope; B*27 and B*57) as well as killer cell immunoglobulin-like receptors have been associated with slow progression of HIV-1 infection. OBJECTIVE: To...

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Bibliographic Details
Main Authors: Edinete Melo da Silva, Angelina Xavier Acosta, Eduardo José Melo Santos, Eduardo Martins Netto, Denise Carneiro Lemaire, Adriano Silva Oliveira, Carolina Matos Barbosa, Maria Teresita Bendicho, Bernardo Galvão-Castro, Carlos Brites
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
HIV
AIDS
MHC
HLA
polymorphism
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500008&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500008&lng=en&tlng=en

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