Expression of VEGF and Flk-1 and Flt-1 Receptors during Blood-Brain Barrier (BBB) Impairment Following Phoneutria nigriventer Spider Venom Exposure

Expression of VEGF and Flk-1 and Flt-1 Receptors during Blood-Brain Barrier (BBB) Impairment Following Phoneutria nigriventer Spider Venom Exposure

Apart from its angiogenic and vascular permeation activity, the vascular endothelial growth factor (VEGF) has been also reported as a potent neuronal protector. Newborn rats with low VEGF levels develop neuron degeneration, while high levels induce protective mechanisms in several neuropathological...

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Bibliographic Details
Main Authors: Monique C. P. Mendonça, Edilene S. Soares, Leila M. Stávale, Catarina Rapôso, Andressa Coope, Evanguedes Kalapothakis, Maria Alice da Cruz-Höfling
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:Toxins
Subjects:
hippocampus
junctional proteins
Neu-N
VEGF
VEGF receptors
Online Access:http://www.mdpi.com/2072-6651/5/12/2572

Internet

http://www.mdpi.com/2072-6651/5/12/2572

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