New Aspects of Neurotransmitter Release and Exocytosis: Involvement of Ca2+/Calmodulin-Dependent Phosphorylation of Synapsin I in Insulin Exocytosis

ABSTRACT: The exocytosis of insulin from pancreatic β-cells is closely related to intracellular elevation of Ca2+. The effects of Ca2+ may be mediated by Ca2+/calmodulin-dependent protein kinase II (CaMKII). Four subunits of CaMKII, termed α, β, γ, and δ, are encoded by distinct genes, and various i...

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Bibliographic Details
Main Authors: Hideyuki Yamamoto, Kazuya Matsumoto, Eiichi Araki, Eishichi Miyamoto
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319326118