Genome-wide survey for biologically functional pseudogenes.

According to current estimates there exist about 20,000 pseudogenes in a mammalian genome. The vast majority of these are disabled and nonfunctional copies of protein-coding genes which, therefore, evolve neutrally. Recent findings that a Makorin1 pseudogene, residing on mouse Chromosome 5, is, inde...

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Bibliographic Details
Main Authors: Orjan Svensson, Lars Arvestad, Jens Lagergren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0020046