Identification of a potent endothelium-derived angiogenic factor.

The secretion of angiogenic factors by vascular endothelial cells is one of the key mechanisms of angiogenesis. Here we report on the isolation of a new potent angiogenic factor, diuridine tetraphosphate (Up4U) from the secretome of human endothelial cells. The angiogenic effect of the endothelial s...

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Bibliographic Details
Main Authors: Vera Jankowski, Markus Tölle, Thi Nguyet Anh Tran, Markus van der Giet, Mirjam Schuchardt, Kerstin Lehmann, Doreen Janke, Burkhard Flick, Alberto Ortiz, Maria D Sanchez-Niño, Martin Tepel, Walter Zidek, Joachim Jankowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726690?pdf=render