Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia

<p>Abstract</p> <p>Background</p> <p>Activation of the peripheral innate immune system stimulates the secretion of CNS cytokines that modulate the behavioral symptoms of sickness. Excessive production of cytokines by microglia, however, may cause long-lasting behavioral...

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Bibliographic Details
Main Authors: Bailey Michael T, Himler Justin, Hanke Mark, Wynne Angela, Huang Yan, Henry Christopher J, Sheridan John F, Godbout Jonathan P
Format: Article
Language:English
Published: BMC 2008-05-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/5/1/15

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http://www.jneuroinflammation.com/content/5/1/15

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