PID1 increases chemotherapy-induced apoptosis in medulloblastoma and glioblastoma cells in a manner that involves NFκB

PID1 increases chemotherapy-induced apoptosis in medulloblastoma and glioblastoma cells in a manner that involves NFκB

Abstract Phosphotyrosine Interaction Domain containing 1 (PID1; NYGGF4) inhibits growth of medulloblastoma, glioblastoma and atypical teratoid rhabdoid tumor cell lines. PID1 tumor mRNA levels are highly correlated with longer survival in medulloblastoma and glioma patients, suggesting their tumors...

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Bibliographic Details
Main Authors: Jingying Xu, Xiuhai Ren, Anup Singh Pathania, G. Esteban Fernandez, Anthony Tran, Yifu Zhang, Rex A. Moats, Gregory M. Shackleford, Anat Erdreich-Epstein
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00947-6

Internet

https://doi.org/10.1038/s41598-017-00947-6

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