Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli.

Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli.

Ileal lesions in Crohn's disease (CD) patients are colonized by pathogenic adherent-invasive Escherichia coli (AIEC) able to adhere to and invade intestinal epithelial cells (IEC), and to survive within macrophages. The interaction of AIEC with IEC depends on bacterial factors mainly type 1 pil...

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Bibliographic Details
Main Authors: Emilie Vazeille, Marie-Agnès Bringer, Aurélie Gardarin, Christophe Chambon, Christoph Becker-Pauly, Sylvia L F Pender, Christine Jakob, Stefan Müller, Daniel Lottaz, Arlette Darfeuille-Michaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21698174/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21698174/pdf/?tool=EBI

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