Hybrid 2-[18F] FDG PET/MRI in premanifest Huntington's disease gene-expansion carriers: The significance of partial volume correction.

<h4>Background</h4>Huntington's disease (HD) is an inherited, progressive neurodegenerative disease that has no cure. Striatal atrophy and hypometabolism has been described in HD as far as 15 years before clinical onset and therefore structural and functional imaging biomarkers are...

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Bibliographic Details
Main Authors: Marie N N Hellem, Tua Vinther-Jensen, Lasse Anderberg, Esben Budtz-Jørgensen, Lena E Hjermind, Vibeke Andrée Larsen, Jørgen E Nielsen, Ian Law
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0252683