Genetic Variants in PGE2 Receptors Modulate the Risk of Nephrosclerosis and Clinical Outcomes in These Patients

Genetic Variants in PGE2 Receptors Modulate the Risk of Nephrosclerosis and Clinical Outcomes in These Patients

Prostaglandin E2 (PGE2) is a major actor mediating renal injury. We aimed to determine genetic variability in the genes coding for its receptors (<i>PTGER1-4</i>) and study associations with nephrosclerosis risk and clinical outcomes. We identified 96 tag-SNPs capturing global variabilit...

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Bibliographic Details
Main Authors: Luz María González, Nicolás Roberto Robles, Sonia Mota-Zamorano, José Manuel Valdivielso, Juan López-Gómez, Guillermo Gervasini
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Personalized Medicine
Subjects:
nephrosclerosis
PGE2
EP receptors
cardiovascular risk
Online Access:https://www.mdpi.com/2075-4426/11/8/772

Internet

https://www.mdpi.com/2075-4426/11/8/772

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