Genetic Variants in PGE2 Receptors Modulate the Risk of Nephrosclerosis and Clinical Outcomes in These Patients
Prostaglandin E2 (PGE2) is a major actor mediating renal injury. We aimed to determine genetic variability in the genes coding for its receptors (<i>PTGER1-4</i>) and study associations with nephrosclerosis risk and clinical outcomes. We identified 96 tag-SNPs capturing global variabilit...
Main Authors: | Luz María González, Nicolás Roberto Robles, Sonia Mota-Zamorano, José Manuel Valdivielso, Juan López-Gómez, Guillermo Gervasini |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Journal of Personalized Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-4426/11/8/772 |
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