Mathematical Modeling of MPNs Offers Understanding and Decision Support for Personalized Treatment

Mathematical Modeling of MPNs Offers Understanding and Decision Support for Personalized Treatment

(1) Background: myeloproliferative neoplasms (MPNs) are slowly developing hematological cancers characterized by few driver mutations, with <i>JAK2</i>V617F being the most prevalent. (2) Methods: using mechanism-based mathematical modeling (MM) of hematopoietic stem cells, mutated hemato...

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Bibliographic Details
Main Authors: Johnny T. Ottesen, Rasmus K. Pedersen, Marc J. B. Dam, Trine A. Knudsen, Vibe Skov, Lasse Kjær, Morten Andersen
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
blood cancer
myeloproliferative neoplasms
<i>JAK2</i>V617F dynamics
mathematical modeling
personalized treatment
Online Access:https://www.mdpi.com/2072-6694/12/8/2119

Internet

https://www.mdpi.com/2072-6694/12/8/2119

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