Strain Prioritization and Genome Mining for Enediyne Natural Products
The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date. Here we report a genome survey of 3,400 actinomycetes, identifying 81 strains that harbor genes encoding the enediyne...
Main Authors: | , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-12-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/7/6/e02104-16 |