Strain Prioritization and Genome Mining for Enediyne Natural Products

Strain Prioritization and Genome Mining for Enediyne Natural Products

The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date. Here we report a genome survey of 3,400 actinomycetes, identifying 81 strains that harbor genes encoding the enediyne...

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Bibliographic Details
Main Authors: Xiaohui Yan, Huiming Ge, Tingting Huang, Hindra, Dong Yang, Qihui Teng, Ivana Crnovčičć, Xiuling Li, Jeffrey D. Rudolf, Jeremy R. Lohman, Yannick Gansemans, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Filip Van Nieuwerburgh, Christoph Rader, Yanwen Duan, Ben Shen
Format: Article
Language:English
Published: American Society for Microbiology 2016-12-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/6/e02104-16

Internet

http://mbio.asm.org/cgi/content/full/7/6/e02104-16

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