An Arginine Deprivation Response Pathway Is Induced in Leishmania during Macrophage Invasion.

An Arginine Deprivation Response Pathway Is Induced in Leishmania during Macrophage Invasion.

Amino acid sensing is an intracellular function that supports nutrient homeostasis, largely through controlled release of amino acids from lysosomal pools. The intracellular pathogen Leishmania resides and proliferates within human macrophage phagolysosomes. Here we describe a new pathway in Leishma...

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Bibliographic Details
Main Authors: Adele Goldman-Pinkovich, Caitlin Balno, Rona Strasser, Michal Zeituni-Molad, Keren Bendelak, Doris Rentsch, Moshe Ephros, Martin Wiese, Armando Jardim, Peter J Myler, Dan Zilberstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4846328?pdf=render

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http://europepmc.org/articles/PMC4846328?pdf=render

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