A systematic evaluation of multi-gene predictors for the pathological response of breast cancer patients to chemotherapy.

Previous studies have reported conflicting assessments of the ability of cell line-derived multi-gene predictors (MGPs) to forecast patient clinical outcomes in cancer patients, thereby warranting an investigation into their suitability for this task. Here, 42 breast cancer cell lines were evaluated...

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Bibliographic Details
Main Authors: Kui Shen, Nan Song, Youngchul Kim, Chunqiao Tian, Shara D Rice, Michael J Gabrin, W Fraser Symmans, Lajos Pusztai, Jae K Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3504014?pdf=render