Automation of Infectious Focus Assay for Determination of Filovirus Titers and Direct Comparison to Plaque and TCID<sub>50</sub> Assays

Automation of Infectious Focus Assay for Determination of Filovirus Titers and Direct Comparison to Plaque and TCID<sub>50</sub> Assays

Ongoing efforts to develop effective therapies against filoviruses rely, to different extents, on quantifying the amount of viable virus in samples by plaque, TCID<sub>50</sub>, and focus assays. Unfortunately, these techniques have inherent variance, and laboratory-specific preferences...

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Bibliographic Details
Main Authors: Patrick T. Keiser, Manu Anantpadma, Hilary Staples, Ricardo Carrion, Robert A. Davey
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Microorganisms
Subjects:
plaque assay
TCID<sub>50</sub>
FFU
filovirus
Ebola
Marburg virus
Online Access:https://www.mdpi.com/2076-2607/9/1/156

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https://www.mdpi.com/2076-2607/9/1/156

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