YY1 mediates TGF-β1-induced EMT and pro-fibrogenesis in alveolar epithelial cells

YY1 mediates TGF-β1-induced EMT and pro-fibrogenesis in alveolar epithelial cells

Abstract Pulmonary fibrosis is a chronic, progressive lung disease associated with lung damage and scarring. The pathological mechanism causing pulmonary fibrosis remains unknown. Emerging evidence suggests prominent roles of epithelial–mesenchymal transition (EMT) of alveolar epithelial cells (AECs...

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Bibliographic Details
Main Authors: Chuyi Zhang, Xiaoping Zhu, Yifei Hua, Qian Zhao, Kaijing Wang, Lixiao Zhen, Guangxue Wang, Jinhui Lü, An Luo, William C. Cho, Xin Lin, Zuoren Yu
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Respiratory Research
Subjects:
YY1
Pulmonary fibrosis
EMT, alveolar epithelial cells
Online Access:http://link.springer.com/article/10.1186/s12931-019-1223-7

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http://link.springer.com/article/10.1186/s12931-019-1223-7

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