Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas

Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas

Background Pediatric high-grade gliomas (pHGGs) are among the most common and incurable malignant neoplasms of childhood. Despite aggressive, multimodal treatment, the outcome of children with high-grade gliomas has not significantly improved over the past decades, prompting the development of innov...

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Bibliographic Details
Main Authors: Malcolm K Brenner, Valentina Hoyos, Ignazio Caruana, Gerrit Weber, Claudia Manuela Arnone, Vinicia Assunta Polito, Angela Mastronuzzi, Andrea Carai, Francesca Camassei Diomedi, Laura Antonucci, Maria Vinci, Francesco Ferrari, Elisa Salviato, Marco Scarsella, Cristiano De Stefanis, Lucia Lisa Petrilli
Format: Article
Language:English
Published: BMJ Publishing Group 2021-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/5/e001930.full

Internet

https://jitc.bmj.com/content/9/5/e001930.full

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