Hispolon Decreases Melanin Production and Induces Apoptosis in Melanoma Cells through the Downregulation of Tyrosinase and Microphthalmia-Associated Transcription Factor (MITF) Expressions and the Activation of Caspase-3, -8 and -9

Hispolon Decreases Melanin Production and Induces Apoptosis in Melanoma Cells through the Downregulation of Tyrosinase and Microphthalmia-Associated Transcription Factor (MITF) Expressions and the Activation of Caspase-3, -8 and -9

Hispolon is one of the most important functional compounds that forms Phellinus linteus (Berkeley & Curtis) Teng. Hispolon has antioxidant, anti-inflammatory, antiproliferative and anticancer effects. In this study, we analyzed the functions of hispolon on melanogenesis and apoptosis in B16...

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Bibliographic Details
Main Authors: Yi-Shyan Chen, Shu-Mei Lee, Chih-Chien Lin, Chia-Yi Liu
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
caspase
hispolon
melanin
microphthalmia-associated transcription factor (MITF)
tyrosinase
Online Access:http://www.mdpi.com/1422-0067/15/1/1201

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http://www.mdpi.com/1422-0067/15/1/1201

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