The Ectopic Expression of Meiosis Regulatory Genes in Cutaneous T-Cell Lymphomas (CTCL)

The Ectopic Expression of Meiosis Regulatory Genes in Cutaneous T-Cell Lymphomas (CTCL)

Cancer testis (CT) antigens, under normal circumstances are uniquely expressed in testicular germ cells. Recent research has shown that meiosis-specific CT (meiCT) antigens are ectopically expressed in cutaneous T-cell lymphoma (CTCL) and may contribute to increased genomic instability. The aberrant...

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Bibliographic Details
Main Authors: Jennifer Gantchev, Amelia Martínez Villarreal, Pingxing Xie, Philippe Lefrançois, Scott Gunn, Elena Netchiporouk, Denis Sasseville, Ivan V. Litvinov
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Oncology
Subjects:
mycosis fungoides (MF)
Sézary Syndrome (SS)
cutaneous T-cell lymphomas (CTCL)
cancer/testis antigens
germ cell proteins
meiCT
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00429/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00429/full

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