SiRNA silencing efficacy prediction based on a deep architecture
Abstract Background Small interfering RNA (siRNA) can be used to post-transcriptional gene regulation by knocking down targeted genes. In functional genomics, biomedical research and cancer therapeutics, siRNA design is a critical research topic. Various computational algorithms have been developed...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-09-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-018-5028-8 |