SiRNA silencing efficacy prediction based on a deep architecture

Abstract Background Small interfering RNA (siRNA) can be used to post-transcriptional gene regulation by knocking down targeted genes. In functional genomics, biomedical research and cancer therapeutics, siRNA design is a critical research topic. Various computational algorithms have been developed...

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Bibliographic Details
Main Authors: Ye Han, Fei He, Yongbing Chen, Yuanning Liu, Helong Yu
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-018-5028-8