Hepatitis B virus s protein enhances sperm apoptosis and reduces sperm fertilizing capacity in vitro.

OBJECTIVE: Studying the impact of Hepatitis B virus S protein (HBs) on early apoptotic events in human spermatozoa and sperm fertilizing capacity. METHODOLOGY/PRINCIPAL FINDINGS: Spermatozoa were exposed to HBs (0, 25, 50, 100 µg/ml) for 3 h, and then fluo-4 AM calcium assay, Calcein/Co(2+) assay, p...

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Bibliographic Details
Main Authors: Jihua Huang, Ying Zhong, Xiaowu Fang, Qingdong Xie, Xiangjin Kang, Riran Wu, Fangzheng Li, Xiaoqin Xu, Hui Lu, Lan Xu, Tianhua Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3712947?pdf=render