Highly selective Diels–Alder and Heck arylation reactions in a divergent synthesis of isoindolo- and pyrrolo-fused polycyclic indoles from 2-formylpyrrole

Highly selective Diels–Alder and Heck arylation reactions in a divergent synthesis of isoindolo- and pyrrolo-fused polycyclic indoles from 2-formylpyrrole

A highly regio-, chemo- and stereoselective divergent synthesis of isoindolo- and pyrrolo-fused polycyclic indoles is herein described, starting from 2-formylpyrrole and employing Diels–Alder and Heck arylation reactions. 3-(N-Benzyl-2-pyrrolyl)acrylates and 4-(pyrrol-2-yl)butenones underwent a high...

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Bibliographic Details
Main Authors: Carlos H. Escalante, Eder I. Martínez-Mora, Carlos Espinoza-Hicks, Alejandro A. Camacho-Dávila, Fernando R. Ramos-Morales, Francisco Delgado, Joaquín Tamariz
Format: Article
Language:English
Published: Beilstein-Institut 2020-06-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
endo-diels–alder stereocontrol
2-formylpyrrole
intramolecular heck arylation reaction
non-covalent interactions
pyrroloindoles
pyrroloisoindoles
Online Access:https://doi.org/10.3762/bjoc.16.113

Internet

https://doi.org/10.3762/bjoc.16.113

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