Induction of diabetes in cynomolgus monkey with one shot of analytical grade streptozotocin

Abstract Backgrounds Streptozotocin (STZ)‐ induced diabetic monkey is a wide used preclinical animal model for the investigation of diabetes such as islet transplantation and development of diabetic drugs. There are serious side effects of this method, including nausea, emesis, weight loss, liver da...

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Bibliographic Details
Main Authors: Zhengzhao Liu, Ying Lu, Wenbao Hu, Hidetaka Hara, Yifan Dai, Zhiming Cai, Lisha Mou
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Animal Models and Experimental Medicine
Subjects:
STZ
Online Access:https://doi.org/10.1002/ame2.12109