Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages

<p>Abstract</p> <p>Background</p> <p>The major risk factor for the development of COPD is cigarette smoking. Smoking causes activation of resident cells and the recruitment of inflammatory cells into the lungs, which leads to release of pro-inflammatory cytokines, chemo...

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Bibliographic Details
Main Authors: De Kimpe Sjef J, Hosseini Hossein, Smit Joost J, Mortaz Esmaeil, Sarir Hadi, Karimi Khalil, Nijkamp Frans P, Folkerts Gert
Format: Article
Language:English
Published: BMC 2006-04-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/7/1/66