PD-L1 Dependent Immunogenic Landscape in Hot Lung Adenocarcinomas Identified by Transcriptome Analysis

PD-L1 Dependent Immunogenic Landscape in Hot Lung Adenocarcinomas Identified by Transcriptome Analysis

Background: Lung cancer is the most frequent cause of cancer-related deaths worldwide. The clinical development of immune checkpoint blockade has dramatically changed the treatment paradigm for patients with lung cancer. Yet, an improved understanding of PD-1/PD-L1 checkpoint blockade-responsive bio...

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Bibliographic Details
Main Authors: Jutta Kirfel, Christiane Charlotte Kümpers, Anke Fähnrich, Carsten Heidel, Mladen Jokic, Ignacija Vlasic, Sebastian Marwitz, Torsten Goldmann, Helen Pasternack, Sabine Bohnet, Danny Jonigk, Mark P. Kühnel, Anne Offermann, Hauke Busch, Sven Perner
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
programmed cell death-ligand 1 (PD-L1)
lung adenocarcinoma (LUAD)
hot
cold
immune phenotype
transcriptome
Online Access:https://www.mdpi.com/2072-6694/13/18/4562

Internet

https://www.mdpi.com/2072-6694/13/18/4562

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