Cell-specific targeting by engineered M13 bacteriophage expressing VEGFR2 nanobody

Cell-specific targeting by engineered M13 bacteriophage expressing VEGFR2 nanobody

Objective(s): Filamentous bacteriophage M13 was genetically engineered to specifically target mammalian cells for gene delivery purpose. Materials and Methods: A vascular endothelial growth factor receptor 2 (VEGFR2)-specific nanobody was genetically fused to the capsid gene III of M13 bacteriophage...

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Bibliographic Details
Main Authors: Farideh Ranjibar, Mahdi Habibi-Anbouhi, Fatemeh Kazemi-Lomedasht, Seyed Hamid Aghaee-Bakhtiyari, Ehsan Alirahimi, Mahdi Behdani
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Bacteriophage
Nanobody
Receptor-mediated gene transfer
Targeted-gene delivery
VEGFR2
Online Access:http://ijbms.mums.ac.ir/article_11206_95e5f8b7d94c3412373ce719195ec23e.pdf

Internet

http://ijbms.mums.ac.ir/article_11206_95e5f8b7d94c3412373ce719195ec23e.pdf

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