The R148.3 Gene Modulates Caenorhabditis elegans Lifespan and Fat Metabolism

The R148.3 Gene Modulates Caenorhabditis elegans Lifespan and Fat Metabolism

Despite many advances, the molecular links between energy metabolism and longevity are not well understood. Here, we have used the nematode model Caenorhabditis elegans to study the role of the yet-uncharacterized gene R148.3 in fat accumulation and lifespan. In wild-type worms, a R148.3p::GFP repor...

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Bibliographic Details
Main Authors: Catherine Roy-Bellavance, Jennifer M. Grants, Stéphanie Miard, Kayoung Lee, Évelyne Rondeau, Chantal Guillemette, Martin J. Simard, Stefan Taubert, Frédéric Picard
Format: Article
Language:English
Published: Oxford University Press 2017-08-01
Series:G3: Genes, Genomes, Genetics
Subjects:
daf-2
R148.3
insulin signaling
lifespan
fat metabolism
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.041681

Internet

http://g3journal.org/lookup/doi/10.1534/g3.117.041681

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