Molecular characterization of spontaneous mesenchymal stem cell transformation.

BACKGROUND: We previously reported the in vitro spontaneous transformation of human mesenchymal stem cells (MSC) generating a population with tumorigenic potential, that we termed transformed mesenchymal cells (TMC). METHODOLOGY/PRINCIPAL FINDINGS: Here we have characterized the molecular changes as...

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Bibliographic Details
Main Authors: Daniel Rubio, Silvia Garcia, Maria F Paz, Teresa De la Cueva, Luis A Lopez-Fernandez, Alison C Lloyd, Javier Garcia-Castro, Antonio Bernad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2151133?pdf=render