The Effect of Trichostatin-A and Tumour Necrosis Factor on Expression of Splice Variants of the MaxiK and L-Type Channels in Human Myometrium
The onset of human parturition is associated with up-regulation of pro-inflammatory cytokines including TNF as well as changes in ion flux, principally Ca2+ and K+, across the myometrial myocytes membrane. Elevation of intra-cellular Ca2+ from the sarcoplasmic reticulum opens L-type Ca2+ channels; i...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-07-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00261/full |